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What is Mesothelioma?

Mesothelioma is a form of cancer that is almost always caused by previous exposure to asbestos. In this disease, malignant cells develop in the mesothelium, a protective lining that covers most of the body's internal organs.

Its most common site is the pleura (outer lining of the lungs and internal chest wall), but it may also occur in the peritoneum (the lining of the abdominal cavity), the pericardium (a sac that surrounds the heart) or tunica vaginalis.

Most people who develop mesothelioma have worked on jobs where they inhaled asbestos particles, or they have been exposed to asbestos dust and fiber in other ways.

ScienceDaily: Mesothelioma News

ScienceDaily: Mesothelioma News

New Clinical Trial For Patients With Asbestos-associated Lung Cancer
25 Jun 08, 11:06:00
The Mesothelioma Center within the Herbert Irving Comprehensive Cancer Center at NewYork-Presbyterian Hospital and Columbia University Medical Center is now recruiting patients for a clinical research study of a new targeted radiation and chemotherapy protocol for pleural mesothelioma, a cancer of the lung's lining that is almost always caused by previous exposure to asbestos.
Carbon Nanotubes That Look Like Asbestos, Behave Like Asbestos, Could Lead To Asbestos-related Disease
22 May 08, 01:05:00
A major study in Nature Nanotechnology suggests some forms of carbon nanotubes -- a poster child for the nanotechnology revolution -- could be as harmful as asbestos if inhaled in sufficient quantities.
Mouse Model For Mesothelioma Reproduces Human Disease
11 Mar 08, 04:03:00
Scientists have established a mouse model for human malignant mesothelioma that will provide valuable insight into cancer development and progression along with new directions for design of therapeutic strategies. The research may eventually lead to a substantially improved outlook for patients with this devastating disease. Malignant mesothelioma is an aggressive cancer originating from the mesothelial lining of the pleural cavity and is associated with asbestos exposure and is characterized by a long latency period between exposure and disease onset.
Asbestos Disease Projections Too Low
04 Apr 07, 04:04:00
Current predictions of the future incidence of asbestos-related disease have been substantially underestimated, according to new modelling to be presented in Melbourne today by an epidemiologist from the Australian National University.
Mesothelioma: Chemo Combination Improves Survival In Asbestos-related Cancer
11 Feb 07, 04:02:00
People with mesothelioma -- a form of cancer associated with asbestos exposure -- have a higher survival rate when treated with a combination of two cancer drugs, a large multicenter study finds.

More on Mesothelioma

Even washing the clothes of a family member who worked with asbestos can be all that it takes.

Unlike lung cancer, there is no association between mesothelioma and smoking. Compensation via asbestos funds or lawsuits is an important issue in mesothelioma.

The symptoms of mesothelioma include shortness of breath due to pleural effusion (fluid between the lung and the chest wall) or chest wall pain, and general symptoms such as weight loss.

The diagnosis may be suspected with chest X-ray and CT scan, and is confirmed with a biopsy (tissue sample) and microscopic examination. A thoracoscopy (inserting a tube with a camera into the chest) can be used to take biopsies. It allows the introduction of substances such as talc to obliterate the pleural space (called pleurodesis), which prevents more fluid from accumulating and pressing on the lung.

Despite treatment with chemotherapy, radiation therapy or sometimes surgery, the disease carries a poor prognosis.

Research about screening tests for the early detection of mesothelioma is ongoing.